If osteomyelitis is suspected, additional imaging is indicated with a combination of plain radiographs, magnetic resonance imaging, and bone scintigraphy.
Therapy for diabetic foot ulcer
The treatment of osteomyelitis requires systemic antibiotic therapy and, in many cases, surgical removal of infected bone.
Localized gangrene of a toe that is not associated with infection may be allowed to self-amputate.
Extensive gangrene is a medical urgency that requires hospitalization, treatment of the underlying infection, optimizing glycemic control, vascular assessment, and consultation with vascular and orthopedic surgeons.