Refrain from picking, squeezing, or trying to pop either an epidermoid cyst or sebaceous cyst. This can increase the risk of infection and scarring. Also, never pick, squeeze or attempt to pop a cystic acne. This drives the infection deeper and increases the risk of scar tissue.
Allow an epidermoid cyst to drain naturally. Once it begins to drain, cover it with a sterile dressing, which you can change twice a day. If a large amount of pus begins to drain from the cyst, the skin surrounding the cyst turns red, the area becomes warm and tender, or blood begins to drain from the cyst, it is time to seek medical care.
Keep the area clean. To prevent an infection, keep the cyst and the area surrounding it clean. Wash it daily using an antibacterial soap or cream.